An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”
Permanent Link for Entry #13391
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Development and use of personalized bacteriophage-therapeutic cocktails to treat a patient with a disseminated resistant Acinetobacter baumannii Infection.Antimicrobial Agents and Chemotherapy, 61, e00954-17, 2017.Order of authorship in the original paper: Schooley, Biswas, Gill .... Successful experimental treatment of a highly antibiotic resistant Acinetobacter baumannii infection by bacteriophage therapy. "In 2016, while serving as the Head of the Division of Infectious Diseases at the UC San Diego School of Medicine, Schooley was approached by his colleague, Dr. Steffanie Strathdee, to help save her husband's life by using bacteriophages (phages). Strathdee's husband, Dr. Tom Patterson, was suffering from a life-threatening multi-drug resistant Acinetobacter baumannii infection, that he had acquired while on vacation in Egypt. Schooley, acting as the primary infectious disease physician, along with Strathdee and a team of researchers and physicians from Texas A&M University, Adaptive Phage Therapeutics, the US Navy, UC San Diego School of Medicine, and San Diego State University, worked together to source, purify and administer phages that were active against the strain of bacteria with which Patterson was infected. Schooley was responsible for successfully navigating the Food and Drug Administration's emergency investigational new drug process, to obtain approval to administer the experimental therapy. After multiple phage cocktail administrations, provided from the partnering laboratories and companies, Patterson was cured of his infection and eventually made a full recovery" (Wikipedia article on Robert T. Schooley). Steffanie Strathdee and Thomas L. Patterson published a book on this case and its cure: The perfect predator: A scientist's race to save her husband from a deadly superbug. New York: Hachette Books, 2019. Digital facsimile of the 2017 paper from PubMedCentral at this link. (Thanks to Juan Weiss for this reference and its interpretation.) Subjects: PHARMACOLOGY › Drug Resistance, PHARMACOLOGY › Phage Therapy Permalink: www.historyofmedicine.com/id/13391 |