An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”
Permanent Link for Entry #14069
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Programmable base editing of A-T to G-C.Nature, 551, 464-480, 2017.Order of authorship in the original publication: Gaudelli, Komor, Rees....Liu. Liu and colleagues developed an advanced CRISPR system that can edit pairings of DNA nucleotide bases Adenine and Thymine into Guanine and Cytosine. In order to achieve this they created a new enzyme in the lab to chemically convert and work on the above pairings. They called this enzyme a "base editor." In theory this tool would enable this improved CRISPR able to target a substantial fraction of SNPs (Single-nucleotide polymorphisms) associated with human genetic diseases. (Thanks to Juan Weiss for this reference and its interpretation.) Subjects: BIOLOGY › MOLECULAR BIOLOGY › CRISPR Gene Editing, WOMEN, Publications by › Years 2000 - Permalink: www.historyofmedicine.com/id/14069 |