An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”
15895 entries, 13848 authors and 1929 subjects. Updated: June 2, 2023
Permanent Link for Entry #16247
Chromatin structure: A repeating unit of histones and DNA.Science, 184, 868-871, 1974.
While a postdoctoral fellow working with Aaron Klug and Francis Crick at the MRC in the 1970s, Kornberg discovered the nucleosome as the basic protein complex packaging chromosomal DNA in the nucleus of eukaryotic cells. Chromosomal DNA is often termed "Chromatin" when it is bound to proteins in this manner, reflecting Walther Flemming's discovery that certain structures within the cell nucleus would absorb dyes and become visible under a microscope.
Subjects: BIOLOGY › Cell Biology, BIOLOGY › MOLECULAR BIOLOGY