An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15875 entries, 13820 authors and 1929 subjects. Updated: March 31, 2023

DONNÉ, Alfred François

2 entries
  • 5207

Animalcules observés dans les matières purulentes et le produit des sécrétions des organes génitaux de l’homme et de la femme.

C. R. Acad. Sci. (Paris), 3, 385-86, Paris, 1836.

First description of Trichomonas vaginalis, which Donné at first believed to be the pernicious agent in gonorrhoea. He later admitted the organism to be a normal inhabitant of the female genital tract. Donné was, by this work, the first to describe living organisms in pathological conditions, as observed by modern methods. English translation in Kean (No. 2268.1).

  • 267.1
  • 3060.1

Cours de microscopie. 1 vol. and atlas.

Paris: J.-B. Baillière, 18441845.

Donne's and Foucault's work was the first biomedical textbook to be illustrated with images made from photomicrographs, in this case daguerreotypes of blood cells. Among its noteworthy images are the first microphotographs of human blood cells and platelets, and the first photographic illustration of Trichomonas vaginalis, the protozoon responsible for vaginal infections, which Donné had discovered in 1836. The text volume of the Cours contains the first description of the microscopic appearance of leukemia, which Donné had observed in blood taken from both an autopsy and a living patient. His observations mark the first time that leukemia was linked with abnormal blood pathology. Foucault, who later achieved fame as a physicist, initally studied medicine, which he abandoned for physics due to an extreme fear of blood. Foucault initially directed his attention to the improvement of Louis Daguerre's photographic processes. For three years he was experimental assistant to Donné in his course of lectures on microscopy.


Subjects: HEMATOLOGY, HEMATOLOGY › Blood Disorders, IMAGING › Photography / Photomicrography , MICROBIOLOGY, Microscopy, OBSTETRICS & GYNECOLOGY › GYNECOLOGY, ONCOLOGY & CANCER › Leukemia