An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15872 entries, 13813 authors and 1928 subjects. Updated: March 23, 2023


1 entries
  • 5279

Report on trypanosomes, trypanosomiasis, and sleeping sickness, being an experimental investigation into their pathology and treatment.

London: Williams & Norgate, 1905.

Thomas and Breinl discovered that arsanilic acid, was more potent in the treatment of laboratory trypanosomiasis than arsenic in inorganic form. As a crystalline powder it was introduced medically as Atoxyl. Thomas and Breinl recommended high doses, given continously for human typanosomiasis. The above is Memoir XVI of the Liverpool School of Tropical Medicine. The drug was soon found to be prohbitively toxic for human use and taken off the market.

Subjects: INFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Tsetse Fly-Borne Diseases › Sleeping Sickness (African Trypanosomiasis), PARASITOLOGY › Trypanosoma, PHARMACOLOGY › PHARMACEUTICALS › Antiparasitic Drugs, TROPICAL Medicine