An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15897 entries, 13853 authors and 1929 subjects. Updated: June 8, 2023

BONA, Constantin A.

1 entries
  • 13472

Defining criteria for autoimmune diseases (Witebsky's postulates revisited).

Immunol. Today, 14, 436-30, 1993.

In 1993 Rose and Bona revised Witebsky's postulates "based on direct evidence from transfer of pathogenic antibody or pathogenic T-cells, indirect evidence based on reproduction of the autoimmune disease in experimental animals and circumstantial evidence from clinical clues.:[5]

  • Auto-antibodies detectable in all cases of disease.
  • Experimentally reproducible by immunization with antigen.
  • Experimental disease must show immunopathological lesions that parallel those in the natural disease.
  • Transferable by serum or lymphoid cells." (Wikipedia article on Ernst Witebsky, accessed 8-2021).