An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16077 entries, 14165 authors and 1948 subjects. Updated: May 6, 2025

TATUM, Edward Lawrie

2 entries
  • 254.3

Genetic control of biochemical reactions in Neurospora.

Proc. Nat. Acad. Sci. (U.S.A.), 27, 499-506, 1941.

Beadle and Tatum proposed the "one gene, one enzyme" hypothesis in 1941. This was a restatement of ideas originally proposed by Archibald Garrod (No. 244.1) in 1908.

1958 Beadle and Tatum shared the Nobel Prize in Physiology or Medicine with Joshua Lederberg (No. 255.4) "for their discovery that genes act by regulating definite chemical events."



Subjects: BIOLOGY › MOLECULAR BIOLOGY, GENETICS / HEREDITY, NOBEL PRIZES › Nobel Prize in Physiology or Medicine
  • 255.4

Gene recombination in Escherichia coli.

Nature, 158, 558, 1946.

Discovery of sexual processes in the reproduction of bacteria.

In 1958 Lederberg shared the Nobel Prize in Physiology or Medicine with Tatum and Beadle (No. 254.3) "for his discoveries concerning genetic recombination and the organization of the genetic material of bacteria."



Subjects: BACTERIOLOGY › BACTERIA (mostly pathogenic; sometimes indexed only to genus) › Gram-Negative Bacteria › Escherichia coli, GENETICS / HEREDITY, NOBEL PRIZES › Nobel Prize in Physiology or Medicine