An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16011 entries, 14068 authors and 1941 subjects. Updated: June 22, 2024

D'HÉRELLE, Félix Hubert

3 entries
  • 2572

Sur une microbe invisible antagoniste des bacilles dysentérique.

C. R. Acad. Sci. (Paris), 165, 373-75, 1917.

d'Herrelle discovered a microbe-eating virus that he called "bacteriophage." He made his discovery independently of the work of Frederick Twort, which was published two years earlier. (See No. 2571). 

  • 10196

Le bactériophage: Son rôle dans l'immunité.

Paris: Masson & Cie, 1921.

D'Hérrelle cited several actual reports of successful treatment of bacterial infections by the injection of bacteriophages in animals and humans. These may be considered early attempts at direct gene transfer in vivo (Wolff & Lederberg p. 11). The advent of antibiotics discouraged further investigation in this direction. Translated into English by George H. Smith as The bacteriophage: Its role in immunity. Baltimore: Williams & Wilkins, 1922. Digital facsimile of the 1921 edition from Google Books at this link, of the English translation at this link.

Subjects: GENETICS / HEREDITY › Gene Therapy / Human Gene Transfer, IMMUNOLOGY, VIROLOGY, VIROLOGY › Bacteriophage
  • 14003

Le bactériophage et son comportement.

Paris: Masson & Cie, 1926.

In this book d'Hérelle reported on the results of quantitative work based on the plaque-count, and dilution methods of assay that he invented. He described a three-step process for the life history of the bacteriophage virus: 1. Attachment to the susceptible bacterium, 2. Multiplication in the cell, 3. Disintegration of the cell to free the progreny virus particles and attachment of the progreny to other susceptible bacteria, if they are present.
English translation as The bacteriophage and its behavior. Baltimore: Williams & Wilkins Co., 1926. 

Subjects: VIROLOGY › Bacteriophage