Discouraged by the high mortality of intussusception, Hirschsprung instituted a plan of controlled hydrostatic pressure reduction. By 1905 he was able to present a 35 per cent mortality based on 107 personal cases in a disease that was usually fatal in over 80 per cent of cases.

Hirschsprung’s diseases (congenital megacolon).

Hirschsprung first made the medical world aware of congenital hypertrophic pyloric stenosis as a distinct clinical entity. In this paper he made no suggestions concerning therapy.