An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: March 22, 2024

SEUNG, Hyunjune Sebastian

1 entries
  • 12751

Eyewire: A game to map the brain.

Princeton, NJ: Sebastian Seung's Laboratory, 2012.

https://eyewire.org/explore

Eyewire is a game to map the brain from Sebastian Seung's Lab at Princeton University. This citizen science human-based computation game challenges players to map retinal neurons. Eyewire launched on December 10, 2012. Over five years, 250,000 people from 150 countries have signed up.
 
Eyewire challenges players, "Eyewirers", to map neurons in 3D. Upon registering, players are directed through a tutorial that explains the game. Supplementary video tutorials are available on the Eyewire Blog.

In Eyewire, the player is given a cube with a partially reconstructed neuron branch stretching through it. On the right side of the screen is a grayscale image of the cross sections of neurons. The player learns to "color" inside a gray outline of a single neuron branch, which usually extends from one side of the cube to another. As a player colors, segmentations that were generated by AI are added to the 3D section on the left of the screen. Reconstructions are compared across players as each cube is submitted, yielding a consensus reconstruction that is later checked by expert players of rank Scout and Scythe. These players have the power to extend branches, remove erroneous segments (nicknamed "mergers"), and flag cubes for further review. This end result is volumetric reconstructions of complete neurons.




Subjects: ANATOMY › Neuroanatomy › Cytoarchitecture, COMPUTING/MATHEMATICS in Medicine & Biology, DIGITAL RESOURCES › Digital Collaborations Online (Wikis), NEUROSCIENCE › Computational Neuroscience › Connectomics