Wagner von Jauregg’s first studies of the effect of fevers upon psychotic conditions. See also No. 4806.

In 1917 Wagner von Jauregg returned to the idea of the inoculation of paretics with malaria to induce pyrexia, first proposed by him in 1887 (Ueber die Einwirkung fieberhafter Erkrankungen auf Psychosen, Jb. Psychiat., 7, 94-131). He was awarded the Nobel Prize in 1927 for his use of pyrotherapy in treating neurosyphilitics. See Magda Whitrow, "Wagner-Jauregg and fever therapy," Medical History, 34 (1990) 294-310.