An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: March 22, 2024

CLARKE, Louise B.

1 entries
  • 13972

A colony bank containing synthetic Col El hybrid plasmids representative of the entire E. coli genome.

Cell, 9, 91-99, 1976.

First description of a "complete" genomic library. This paper includes the Carbon-Clarke equation used for calculating the number of clones required when constructing a clone library to ensure a given probability (usually > 99% is desired) of containing any sequence, given the size of the genome and the average size of a clone.



Subjects: BIOLOGY › MOLECULAR BIOLOGY › Genomics