An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15895 entries, 13848 authors and 1929 subjects. Updated: June 2, 2023

ALPERS, Michael

1 entries
  • 13914

Attempts to demonstrate a transmissible agent in Kuru, Amyotrophic Lateral Sclerosis, and other subacute and chronic progressive nervous system degenerations in man. Addendum p. 46 in: Slow, latent, and temperate virus infections. NINDB Monograph No. 2. Edited by D. Carleton Gajdusek, Clarence J. Gibbs, Jr., and Michael Alpers.

Washington, DC: U.S. Department of Health, Education, and Welfare, 1965.

In their Addendum on p. 46 the authors stated that 20 and 21 months post innocculation in the brain with brain material from Kuru patients two chimpanzees showed symptoms of an illness suggestive of Kuru. Digital facsimile from Google Books at this link.

The authors formally reported these results the following year in Gajdusek, Gibbs, & Alpers, "Experimental transmission of a Kuru-like syndrome to chimpanzees," Nature, 209 (1966), 794-96.

(Thanks to Juan Weiss for this reference and its interpretation.)

Subjects: INFECTIOUS DISEASE › Prion Diseases, NEUROLOGY › Degenerative Disorders