DENIS, Prosper Sylvain
2 entries
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Recherches expérimentales sur le sang human considérè à l'état sain.Paris: Chez les libraires qui tiennent les ouvrages de médecine, 1830.Denis discovered the presence of cholesterol (“cholestérine”) in the blood. This he announced on p. 110 of his Recherches expérimentales. Subjects: HEMATOLOGY, Laboratory Medicine › Blood Tests |
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Mémoire sur le sang quand il est fluide, pendant qu’il se coagule et lorsqu’il est coagulé.Paris: J.-B. Baillière, 1859.The first attempt to isolate and describe fibrinogen, the blood protein essential for clotting. “Prosper-Sylvain Denis, in his Mémoire sur le sang (1859), was the first to recognize that plasma contained a clottable substance, not defined as a liquid fibrin, but different from fibrin, and he attempted to purify and characterize this protein. He independently proposed the name fibrinogène” (Rosenfeld, Four Centuries of Clinical Chemistry, p. 438). Subjects: HEMATOLOGY › Coagulation |