An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15999 entries, 14040 authors and 1941 subjects. Updated: June 18, 2024

GADDUM, Sir John Henry

3 entries
  • 1917

The action of adrenalin and ergotamine on the uterus of the rabbit.

J. Physiol. (Lond.), 61, 141-50, 1926.

Gaddum produced concentration-effect curves of antagonistic drugs, showing the dose-ratio linearly related to antagonistic concentration. See also No. 1925.1



Subjects: PHARMACOLOGY, PHARMACOLOGY › Pharmacodynamics
  • 1352

The chemical transmitter at synapses in a sympathetic ganglion.

J. Physiol. (Lond.), 81, 305-19, 1934.

These workers produced evidence that a chemical agent (acetylcholine) appears in the transfer of nerve impulses from neuron to neuron in sympathetic ganglia.



Subjects: NEUROSCIENCE › NERVOUS SYSTEM › Chemical Mediation of Nervous Impulses
  • 1925.1

The quantitative effect of antagonistic drugs

J. Physiol. (Lond.), 89, 7P-9P, 1937.

Gaddum was the first to formulate the theory of competitive drug antagonism. See also No. 1917.



Subjects: PHARMACOLOGY › Pharmacodynamics