An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16027 entries, 14091 authors and 1941 subjects. Updated: August 10, 2024

Permanent Link for Entry #16458

  • 14144

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

J. biol. Chem. , 253, 6401-12, 1978.

Gilman and colleagues showed that G proteins are in the cell membrane and are stimulated once a ligand (adrenaline) binds the adrenergic receptor. This system can then activate adenyl cyclase to form cyclic AMP. Digital facsimile from PubMedCentral at this link.

Order of authorship in the original publication: Ross, Howlett, Ferguson, Gilman.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BIOLOGY › MOLECULAR BIOLOGY › Protein Receptors
Permalink: www.historyofmedicine.com/id/16458