An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15893 entries, 13847 authors and 1929 subjects. Updated: May 25, 2023

MULLIS, Kary Banks

2 entries
  • 10785

Enzymatic amplication of B-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.

Science, 230, 1350-1354, 1985.

Polymerase chain reaction first published. With Randall K. Saiki, Stephen Scharf, Fred Faloona et al. Order of authorship in the original paper was Saiki, Scharf, Faloona, Mullis....

(Thanks to Juan Weiss for this reference.)

Subjects: BIOLOGY › MOLECULAR BIOLOGY › Polymerase Chain Reaction, GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Blood Disorders › Sickle-Cell Disease
  • 7213

Specific enzymatic amplification of DNA in vitro: The polymerase chain reaction.

Cold Spring Harbor Symposium in Quantitative Biology, 51, 263–273, 1986.

Improvements that Mullis made to the polymerase chain reaction in 1983 enabled PCR to become a central technique in biochemistry and molecular biology. The process was first described by Kjell Kleppe and 1968 Nobel laureate H. Gobind Khorana. This was Mullis's first "methods" publication on the topic. With F. Faloona, S. Scharf, R. Saiki, G. Horn and H. Erlich. For this discovery Mullis shared the 1993 Nobel Prize in chemistry.

Subjects: BIOLOGY › MOLECULAR BIOLOGY › Polymerase Chain Reaction