An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: March 22, 2024

WIGLER, Michael Howard

1 entries
  • 13929

Transformation of mammalian cells with genes from procaryotes and eucaryotes.

Cell, 16, 777-75, 1979.

Axel, along with microbiologist Saul J. Silverstein and geneticist Michael H. Wigler, discovered a technique of cotransformation via transfection. This process, which allows foreign DNA to be inserted into a host cell to produce certain proteins, is fundamental to recombinant DNA research at pharamceutical and biotech companies. Order of authorship in the original publication: Wigler, ...Silverstein, Axel.



Subjects: BIOLOGY › MOLECULAR BIOLOGY › Recombinant DNA, Biotechnology