An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15959 entries, 13943 authors and 1935 subjects. Updated: February 28, 2024

HOLLAND, Paul

1 entries
  • 13540

Transmissible agent in non-A, non-B hepatitis.

Lancet,1, 459-463, 1978.

The first paper recording the discovery of what was, eleven years later in 1989, named the hepatitis C virus (see No. 12653). Harvey Alter (Nobel Prize 2020) and colleagues inoculated the serum/plasma of 4 patients with non-A/non-B hepatitis into 5 chimps, and the chimps showed both biochemical and histological evidence of a typical hepatitis. The experiment was performed with a negative control. Order of authorship in the original paper: Alter, Purcell, Holland....

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: VIROLOGY › VIRUSES (by Family) › Hepadnaviridae › Hepatitis C Virus